How the Gut Microbiome Shapes Pain: Histamine, Mast Cells, and IBS

Institute for Systems Biology · 29:52 · Watch on YouTube

Germ-free and patient-microbiota mouse studies indicate that, in a subset of irritable bowel syndrome (IBS), histamine made by gut bacteria—especially *Klebsiella aerogenes*—recruits colonic mast cells through the H4...

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