Rebecca Shapiro: CRISPR screening reveals novel drivers of aneuploidy-mediated antifungal tolerance

Cornell SIPS · 54:56 · Watch on YouTube

Aneuploidy of *Candida albicans* chromosome R creates reversible azole tolerance, and a CRISPRa/i dosage screen shows that two secretory Rab GTPases, *SEC4* and *YPT31*, are together necessary and sufficient for that...

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